Systems Biology Centres

List of centers undertaking Systems Biology in the UK and those from outside the UK working on plant systems biology.

AGRONOMICS Arabidopsis GROwth Network integrating OMICS technologies

EU funded project of several partners that aims to gain a better understanding of leaf growth and regulation. The project ended in April 2012. 

Cambridge Systems Biology Centre

From the website: CSBC has particular strengths in bioinformatics and computer/mathematical modelling, in transcriptomics and proteomics, and in the integration and analysis of large data sets. CSBC aims to translate state-of-the-art systems biology techniques being developed using model organisms to applications in plant science and medicine. CSBC hosts visiting researchers from across the university and the world and provides a friendly, dynamic, and highly interactive environment in which they can successfully pursue their research goals.

CISBAN, Centre for Integrative Systems Biology of Ageing and Nutrition

From the website: CISBAN is a multidisciplinary research centre within Newcastle University. It is particularly closely associated with the Institute for Ageing and Health, but its staff members come mainly from the Faculty of Medical Sciences, the School of Computing Science and the School of Mathematics and Statistics. CISBAN's aim is to advance understanding of the complex mechanisms underpinning the ageing process and of how these are affected by nutrition, through the field of research known as systems biology.

CISBIO, The Centre for Integrative Systems Biology and Bioinformatics

From the website: CISBIO is part of the Institute of Systems and Synthetic Biology (IoSSB) which acts as the overarching strategic body for all Systems and Synthetic Biology activities at Imperial College.

CISBIO brings together scientists from a wide range of different fields to develop innovative interdisciplinary approaches to understanding biological problems. A key component of the interdisciplinary strategy is a repeated cycle of experimentation and modelling.

COMPLEX, UCL Centre of Interdisciplinary Science

From the website: CoMPLEX is UCL’s centre for interdisciplinary research in the medical and life sciences. It brings together life and medical scientists with mathematicians, physical scientists, computer scientists and engineers to tackle the challenges arising from complexity in biology and medicine.

Computable Plant

This project aims to provide a quantitative and cellular description of plant development by studying meristem development in Arabidopsis thaliana.

CPIB, Centre for Plant Integrative Biology

From the website: The Centre for Plant Integrative Biology at the University of Nottingham is a systems biology research centre focussing on mathematical and computational modelling of plants.

CPIB brings together an interdisciplinary team to produce, test and refine multi-cell, multiscale models incorporating molecular networks, 3D geometry, and mechanics.

Institute for Systems Biology

From the website: ISB pioneered systems biology, which harnesses and integrates the respective insights of biologists, geneticists, computer scientists, chemists, engineers, mathematicians, immunologists and others to answer some of society's most challenging questions related to health and the environment. Since 2000, ISB has grown to more than 240 staffers, which includes 11 faculty members and laboratory groups.

Institute of Chemical Biology at Imperial College London

The Institute of Chemical Biology (ICB)'s mission is to support and develop multidisciplinary research crossing the physical sciences-life sciences/biomedical interface. In particular we focus on the development and application of novel tools and technology for solving major problems in the life and biomedical sciences.

There is also a Doctoral Training Centre: Sponsored by the EPSRC and BBSRC, our programme will have taken on 120-140 students by 2013. These students take a 4-year programme starting with a Masters in Research degree following on with a PhD.

MCISB, Manchester Centre for Integrative Systems Biology

From the website: The MCISB is intended to provide a hub for cutting-edge systems biology research in the Manchester area, acting as a focal point for the creation of the necessary ideas and infrastructure, and for establishing new methods and routines.

OCISB, Oxford Centre for Integrative Systems Biology

From the website: We aim to develop theoretical approaches which not only address problems at specific scales, but which bridge scales in a computationally efficient and mathematically tractable way. The approaches will be applied to a range of bacterial and eukaryotic sensory signalling networks, populated with data sets at different levels of completeness. The predictive models that we develop will be used to guide experiments, the results of which will be used to refine the models.


From the website: SynthSys represents an interdisciplinary research environment with members across many Research Institutes, Colleges and Schools, including The University of Edinburgh, Heriot-Watt University and BioSS. The Centre is currently expanding its membership and now includes additional researchers leading grants in related areas.

Universities of Leeds and Sheffield

EPSRC Doctoral Training Centre.

From the website: The Universities of Leeds and Sheffield have combined their strengths in biophysics, biochemistry and bioengineering to offer a new style PhD designed to train scientists with bachelors and masters degrees in physical sciences or engineering subjects to work effectively in this exciting area. 

University of Edinburgh

EPSRC Ddoctoral Training Centre.

From the website: The DTC provides an interdisciplinary programme that trains PhD students in neuroinformatics and computational neuroscience.

University of Oxford
EPSRC Post-doctoral Training Centre

University of Strathclyde

EPSRC Post-doctoral Training Centre

Virtual Plants

The Virtual Plants is an INRIA project-team, joint with CIRAD and INRA. It is located at UMR DAP, Montpellier, France. The long-term focus of the project is to study plant development and its control by genetic processes.

WSBC, Warwick Systems Biology Centre

From the website: Our aim is to improve understanding of complex biological systems so that a broad range of biological and medical priorities, such as disease mechanisms, pharmaceutical drug discovery, drug target validation, and challenges in horticulture and agriculture, can be addressed.