30th Sep 2013

In this week’s Arabidopsis Research Round-Up, we have a new paper from a GARNet committee member, and an interesting statistical method developed and validated in both plant and animal models. Enjoy!


  • Jiang C, Belfield EJ, Cao Y, Smith AC and Harberd NP. An Arabidopsis soil-salinity–tolerance mutation confers ethylene-mediated enhancement of sodium/potassium homeostasis. The Plant Cell, September 2013. DOI: 10.​1105/​tpc.​113.​115659.

Nicholas Harberd, a member of the GARNet advisory committee, and his lab members from the University of Oxford, have identified that knocking out the loss-of-function allele ETHYLENE OVERPRODUCER1 (ETO1) causes excess ethylene production in Arabidopsis thaliana. This, in turn, affects the ETHYLENE RESISTANT1-CONSTITUTIVE TRIPLE RESPONSE1 ethylene signalling pathway, improving Na/K homeostasis in the shoot and conferring transpiration-dependent soil-salinity tolerance.


  • Brennecke P, Anders S, Kim JK et al. Accounting for technical noise in single-cell RNA-seq experiments. Nature Methods, 22 September 2013. DOI: 10.1038/nmeth.2645.

A collaboration of German, UK and Australian scientists working with both plant (Arabidopsis thaliana) and animal (Mus musculus) models present this Nature Methods paper. Here, a novel statistical method is presented for quantifying true biological variability from the high levels of technical noise in single-cell experiments.